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  Coriolus Super Strength, 600mg, 90 vegicaps

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Product Code: 192-1007


Coriolus versicolor VPS: helps Recovery from the anticancer medicines - Enhance the cytotoxic activity of NK cells - Act as a potent inducer tumor cytotoxicity - Stimulate the antigen-presenting cell function of macrophage

Hot water extracts of Coriolus versicolor are one of the most effective and best selling immune support supplements in the world, and the most widely used immune support supplement in Japan.*

The immune health benefits have been verified in hundreds of studies and dozens of human clinical trials, making Coriolus versicolor one of the most thoroughly researched medicinal mushrooms used for immune support.*

Coriolus versicolor is known as Yun zhi in China and Kawaratake in Japan.  In the U.S. it is also known as the Turkey Tail mushroom and by the scientific name Trametes versicolor. Coriolus versicolor is probably the most common shelf fungus in the world.


Over 600 studies have been conducted and published on the immune supporting properties of the 1-4, 1-3, 1-6 linked beta glucans extracted from the cell walls of Coriolus versicolor, including 24 human clinical studies (14 placebo controlled, double-blind, human clinical trials).*

There are no scientific or herbal references supporting the use of un-extracted mycelium powder (mycelium grown on rice), or tinctures (liquid supplements preserved in alcohol, also referred to as cold water extracts ).

If you are intersted in the differences between Coriolus PSP and Coriolus Super Strength please read the science section on the Coriolus PSP product page.


As mentioned in the Product Description area some companies claim that PSK and PSP can only be extracted from the mycelium, not the mushrooms, which is not true according to the U.S. Patent filed by the original inventors of PSK.

It is true that the pharmaceutical company that first manufactured PSK for the Japanese market preferred to extract PSK from mycelium grown through liquid fermentation, also known as submerged culture, because this process does make more sense for their business model. 

The pharmaceutical company already owned the equipment needed to produce the mycelium, the stainless steel fermenters or bio-reactors, and they are able to grow a batch of mycelium in 48-72 hours, producing the raw material quickly, when needed.

It can take up to 4-5 months to grow a crop of Coriolus versiciolor mushrooms on wood.  However, this is the method we prefer.  Wood is what the mushrooms grow on in nature, and it provides a far more complex nutrient base than mycelium grown on rice or grown in liquid.

In the U.S.Patent detailing the extraction process the inventors offered "Proofs" of the extraction process, where they extracted "PSK" from both the mycelium and the mushroom fruit bodies.  However, the PSK extracted from the mushrooms had higher levels of immune activity as compared to the PSK extracted from the mycelium.*


The research shows that the polysaccharide portion of the extract enhances the cell-mediated immune response.* The 1-4, 1-3, 1-6 linked beta glucans that make up the backbone of the polysaccharide molecule act as a biological response modifier and have been found to support and enhance Natural Killer cell function, to stimulate depressed lymphocyte proliferation, and to support the healthy growth of white blood cells.* 

The research also shows these constituents to be effective at supporting normal cell growth, improving cell-mediated cytotoxicity, and increasing interleukin-2 production and T-cell proliferation.* 


The results of an eight-year human clinical study, published in 1990, recorded substantial benefit from the daily use of a Coriolus polysaccharide extract (obtained through hot-water extraction). The group receiving the Coriolus extract experienced significant improvements in immune health as compared to the group receiving the placebo, with the leukocyte activity of the Coriolus group showing “remarkable enhancement.”*

It was concluded that “the beneficial effects were probably due to the activation of leukocyte function as one of the many biological-response-modifying activities induced by Coriolus.” In a study published in Lancet, a Coriolus polysaccharide extract containing the 1-4, 1-3, 1-6 linked beta glucans was found to have a “restorative effect in patients who have been immuno-suppressed.”* 


Hot-water extracts from both the fruit body and the mycelium are used in current clinical practice and the published research. The active constituents, the protein-bound polysaccharides and the polysaccharide peptides, are found in the cell walls of both, although extracts from the fruit body (the mushroom), have shown higher levels of immune activity.*

Coriolus Super Strength is isolated using a multi-step hot-water extraction process, creating the highest possible concentrations of the polysaccharides examined in the Japanese research on PSK.  As these compounds are difficult to extract and easily degraded with excessive heat, NMR and linkage analysis are used to ensure product quality.

Suggested usage: Adults, take 1-3 capsules, twice daily, on an empty stomach.

Warnings: Keep out of reach of children. Do not use if allergic to mushrooms, pregnant or breast feeding. Do not use if safety seal around top of bottle is missing or broken. Store at room temperature, with lid closed.

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